The Reset Firefox feature can fix many issues by restoring Firefox to its factory default state while saving your essential information. Note: This will cause you to lose any Extensions, Open websites, and some Preferences.

To Reset Firefox do the following:

1. Go to Firefox > Help > Troubleshooting Information.
2. Click the "Reset Firefox" button.
3. Firefox will close and reset. After Firefox is done, it will show a window with the information that is imported. Click Finish.
4. Firefox will open with all factory defaults applied.

Further information can be found in the Refresh Firefox - reset add-ons and settings article.

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I imagine this will work. However this equates to the nuclear option for fixing the problem. I have made a number of changes to the about:config file over time to customize firefox and I haven't really kept track of them. Is there an easy way to know/export my changes specifically to the about:config file?

Firefox makes a backup of your old data on your desktop when you reset. In all likelyhood it's your about:config changes that are causing this problem anyway.

I know this question was asked a month ago, but I had the same problem so I thought I would throw this out there. The solution for me was to disable the Realplayer Downloader add-on.

I went down the list one by one, and that is the only one that means the difference between the links working and not working.

I keep it disabled until I need to use it.

Thanks jmd2119. I have to say I figured the answer out just a week or so ago but the Real Player Downloader add-on was absolutely the culprit. Disabling it fixes the problem. I will have to enable it just when I need it. Thanks.

Good to hear that it is a confirmed issue, not just me. Now the harder part is getting RealPlayer or Mozilla aware of the bug.