What kind of settings you would have to be saved? Do you mean parameters in the option tab (= about:preferences in the URL bar)?

Banban said

What kind of settings you would have to be saved? Do you mean parameters in the option tab (= about:preferences in the URL bar)?

Yes! About the fonts setting and which site can be pinned in new tab page This kind of setting i need to setting every time when i restart my computer

Have a look at Firefox profiles description for "User preferences" item. You could try to apply the process described here on the prefs.js file.

Hi, also see - How to fix preferences that won't save.