What site?

It's a support site for e-commerce client that has voice and video chat functionality. The same site works on chrome just fine

That doesn't help me help you...

Here is my mic info and a site asking for permission. see screenshots

If you can provide similar info, that would help us better assist you.

Edition Windows 11 Pro Insider Preview Version 22H2 Installed on ‎21-‎Nov-‎22 OS build 25247.1000 Experience Windows Feature Experience Pack 1000.25247.1000.0

It's possible they changed the site in a way that makes it incompatible, but before going down that road, these are standard suggestions to try when a site that has worked in Firefox suddenly stops working normally:

Double-check content blockers: Firefox's Tracking Protection feature, and extensions that counter ads and tracking, may break websites that embed third party content (meaning, from a secondary server).

(A) The shield icon toward the left end of the address bar usually turns a bit purplish when content is blocked. Click the icon to learn more or make an exception. See: Enhanced Tracking Protection in Firefox for desktop.

(B) Extensions such as Adblock Plus, Blur, Disconnect, DuckDuckGo Privacy Essentials, Ghostery, NoScript, Privacy Badger, uBlock Origin or uMatrix usually provide a toolbar button to manage blocked content in a page. There may or may not be a number on the icon indicating the number of blocked items; you sometimes need to click the button to see what's going on and test whether you need to make an exception for this site.

Cache and Cookies: When you have a problem with one particular site, a good "first thing to try" is clearing your Firefox cache and deleting your saved cookies for the site.

(1) Clear Firefox's Cache

See: How to clear the Firefox cache (only select Cached web content, don't clear all cookies and site data)

If you have a large hard drive, this might take a few minutes.

(2) Remove the site's cookies (save any pending work first). While viewing a page on the site, click the lock icon at the left end of the address bar. After a moment, a "Clear Cookies and Site Data" button should appear at the bottom. Go ahead and click that. Firefox will ask you to confirm; go ahead and confirm.

Then try reloading the page. Does that help?

Testing in Firefox's Troubleshoot Mode: In this mode, Firefox temporarily deactivates extensions, hardware acceleration, any userChrome.css/userContent.css files, and some other advanced features to help you assess whether these are causing the problem.

If Firefox is running:

You can restart Firefox in Troubleshoot Mode using either:

• "3-bar" menu button > Help > Troubleshoot Mode... (before Fx88: Restart with Add-ons Disabled)
• (menu bar) Help menu > Troubleshoot Mode... (before Fx88: Restart with Add-ons Disabled)

and OK the restart. A small dialog should appear. Click the Open button (before Fx88: "Start in Safe Mode" button).

If Firefox is not running:

Hold down the Shift key when starting Firefox. (On Mac, hold down the option/alt key instead of the Shift key.) A small dialog should appear. Click the Open button (before Fx88: "Start in Safe Mode" button).

Note: Don't use the Refresh without first reviewing this article to understand what will be deleted: Refresh Firefox - reset add-ons and settings.

Any improvement?