Hi

Yes, Firefox Quantum should work on a 64bit version of Windows 10.

I installed Firefox 57.0 Quantum three times in WIndows 10 and it was unstable. It would flash up for less than a second and disappear.

There were signs of life to indicate that it was running - but it was unusable. I rebooted - no good. I uninstalled and reinstalled - no good. I finally downloaded and installed 56 from Mozilla then quickly shut down WiFi and disabled auto-updates before it could upgrade to Quantum again. (The first time it automatically started upgrading to 57).

Four hours gone. Another good reason to be cautious about activating auto-updates. I've never had an issue with Firefox until today. Ouch.